Fabien FERRAGE

Nuclear Magnetic Resonance

Fabien FERRAGE

Fabien FERRAGE

Research Director

Nuclear Magnetic ResonanceNuclear Spin RelaxationHigh-resolution relaxometryTwo-field NMRProtein DynamicsIntrinsically disordered proteins

Research Topics

Two-field NMR spectroscopy

Two-field NMR spectroscopy

The complexity of molecular systems accessible to NMR has increased dramatically with the advent of …

Dynamics and interactions of biomolecules by high-resolution relaxometry

Dynamics and interactions of biomolecules by high-resolution relaxometry

Nuclear spin relaxation originates from the fluctuations of interactions due to motions at the molec…

Projects

COMPLETED

Consortium of experimental platforms in Chemistry, Physics and Biology at PSL University for the preparation and characterization of systems from the molecule to nanometric devices and living systems.

COMPLETED

This project complements the equipment acquired in the frame of the Equipex IMF-NMR project by co-funding the purchase of two cryogenic probes on the 900 MHz spectrometer, optimized for proton and carbon-13 detection.

COMPLETED

Investigating how molecular dynamics affects allosteric enzyme activation using experimental and computational methods.

COMPLETED

Understanding the organization, dynamics and mechanics of NHEJ DNA repair condensates and their regulatory interactions.

COMPLETED

A new instrument is developed, installed and exploited at ENS – PSL in the CPCV laboratory, coupling very high-field NMR (900 MHz) with evolution of nuclear spins at low magnetic field. This instrument will be open to the local and national scientific communities in chemistry, structural biology and material sciences.